Important Safety Information
Do not take BETASERON® (interferon beta-1b) if you are allergic to interferon beta-1b, to another interferon beta, to human albumin, or mannitol. See additional Important Safety Information below.


Asked Questions

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Models used for illustrative purposes only.

    What is BETASERON®?

    BETASERON® is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.

    It is not known if BETASERON is safe and effective in children.

    Who should not take BETASERON?

    Do not take BETASERON if you are allergic to interferon beta-1b, to another interferon beta, to human albumin, or mannitol. See Medication Guide for a complete list of ingredients in BETASERON.

    How should I store BETASERON?

    Before mixing, store BETASERON at room temperature between 68°F to 77°F (20°C to 25°C).

    Before mixing, BETASERON may be stored for up to 3 months between 59°F to 86°F (15°C to 30°C).

    After mixing, you can refrigerate BETASERON for up to 3 hours before using. Your BETASERON must be used within 3 hours of mixing even if refrigerated.

    Do not freeze.

    Keep BETASERON and all medicines out of the reach of children.

    What are the ingredients in BETASERON?

    Active ingredient: interferon beta-1b

    Inactive ingredients: albumin (human), mannitol

    Diluent contains sodium chloride solution

    Do I need to disinfect the vial after taking off the cap?

    Use an alcohol prep pad to clean the top of the vial. Move the alcohol prep pad in one direction. Leave the alcohol prep pad on top of the vial. Wipe in one direction only—NOT back and forth—so you don’t spread germs.

    How do I best connect the syringe to the vial adapter?

    Connect the pre-filled diluent syringe to the vial adapter by turning clockwise until resistance is felt and the attachment is secure. This forms the syringe assembly. Taking care not to overtighten, turn the syringe clockwise, no more than 3 turns, until the 2 pieces are securely connected. It doesn’t take much force.

    How do I avoid bubbles and foam when diluting the medication?

    Never shake the vial; it doesn’t speed up the mixing, and it can cause foam to form. If there is foam, let the vial sit until the foam settles before using it.

    Hold the assembled syringe with the vial on the bottom and tilt the vial just slightly to the side. This will help prevent bubbles from forming.

    What do I do with my used syringes?

    Put your used BETASERON syringe and needle in an FDA-cleared sharps disposal container right away after use. Do not throw away (dispose of) your used syringes and needles in your household trash. When the container is full, ask your pharmacist, healthcare provider, or BETA Nurse how to dispose of it.

    Review injection steps


    BETASERON can cause serious side effects, including:

    Liver Problems Including Liver Failure. Symptoms of liver problems may include yellowing of your eyes, itchy skin, feeling very tired, flu-like symptoms, nausea or vomiting, bruising easily or bleeding problems. Your healthcare provider will do blood tests to check for these problems while you take BETASERON.

    Please see additional Important Safety Information below.

    How do I turn on the BETACONNECT autoinjector?

    First, make sure the BETACONNECT autoinjector is fully charged. Then firmly press the on/off button for more than 2 seconds.

    My BETACONNECT autoinjector turns off automatically. What should I do?

    BETACONNECT autoinjector will automatically turn off after 20 minutes of inactivity. Press the on/off button to turn on.

    BETACONNECT autoinjector will power off if the battery level is too low. Recharge your BETACONNECT autoinjector if the battery indicator flashes orange when you turn your device on.

    Can I use the BETACONNECT autoinjector while it’s being charged?

    The BETACONNECT autoinjector will not operate while it is being charged. Fully charge the BETACONNECT autoinjector and remove the charger before use.

    I’m unable to open the lid.

    The lid cannot be opened during the injection process. Wait until the injection process is completed.

    If the lid or the blue lid release button does not function, ask your BETA Nurse or healthcare provider for a replacement.

    I can’t inject by activating the safety release.

    If the safety release does not function, ask your BETA Nurse or healthcare provider for a replacement.

    It is not possible to charge the BETACONNECT autoinjector.

    You might be using the wrong micro-USB cable or charger. Make sure you use the charger and cables that come with your BETACONNECT autoinjector.

    The micro-USB connection could be worn out. Ask your BETA Nurse or healthcare provider for a replacement.

    I can’t insert the syringe into the BETACONNECT autoinjector.

    The wrong syringe type is being used. Use only the syringes that come with your BETASERON.

    The syringe might not be placed into the insertion area correctly. Make sure that the syringe is lined up with the syringe outline in the insertion area.

    The syringe could be prepared incorrectly. Refer to the instructions in the BETASERON Medication Guide, and prepare a new syringe if necessary.

    The plunger is pulled past the "1-mL" mark.

    The green light on the on/off button does not stop blinking after the BETACONNECT autoinjector was turned on.

    The self-test is not completed. Make sure the safety release in the front of the BETACONNECT autoinjector is not pressed. Open the lid and close the lid. Make sure the lid is fully closed. Make sure no buttons are pressed down. Hold the on/off button to shut down BETACONNECT autoinjector, and turn it on again.

    If the problem is not solved, contact your healthcare provider or call a BETA Nurse at 1-844-788-1470.

    A red blinking light is showing on the BETACONNECT autoinjector.

    The injection procedure could have been interrupted. If the injection was interrupted, check to see that the entire dose was injected. If it was not, talk with your BETA Nurse or healthcare provider.

    BETACONNECT™ could be detecting a malfunction. Hold the on/off button down to shut down BETACONNECT autoinjector and turn it on again. If the red blinking light is still there, talk with your healthcare provider or call a BETA Nurse at 1-844-788-1470.

    An orange light is shown on the BETACONNECT autoinjector during charging.

    The temperature is too low or too high for charging. The BETACONNECT autoinjector can be recharged at a temperature from 50°F to 95°F (10°C to 35°C).

    More about BETACONNECT


    BETASERON can cause serious side effects, including:

    Serious Allergic Reactions. Serious allergic reactions can happen quickly and may happen after your first dose of BETASERON or after you have taken BETASERON many times. Symptoms may include difficulty breathing or swallowing, swelling of the mouth or tongue, rash, itching, or skin bumps.

    Please see additional Important Safety Information below.


    Where can I download BETA track, and does it cost anything?

    You can download BETA track onto your smartphone, tablet, or computer. To download BETA track onto your mobile device, install the app from the Apple® App Store® or Google Play™ Store. BETA track is free to use.

    Do I have to be a BETASERON patient to use BETA track?

    Yes, BETA track is intended for BETASERON patients only. Ask your doctor if BETASERON is right for you.

    Do I need an Internet connection to use BETA track?

    No. You don't need an Internet connection to use BETA track. You can also access the app through your data plan.


    Do I need to register to use BETA track?

    No. You will not need to set up an account when you first launch BETA track on your smartphone, tablet, or computer.

    Is my personal and medical information secure?

    Yes. Your personal and medical data is secured with safeguards in place, as described in the Privacy Statement.


    Why should I share my injection data via text, email, or printed PDF?

    When you share your injection data with your BETA Nurse and healthcare team, it will help facilitate your discussion by providing information on your treatment journey.

    Why does my “suggested next injection site” function not include all of the injection sites?

    Confirm that you have not disabled any of the injection sites on the SETTINGS screen. If you have done so, the site’s suggestion function will automatically skip any injection site that you deselected.

    Can I print my recorded injection history from BETA track?

    You can print your recorded injection history using the print feature in your browser on your computer. This list of recorded injections has been formatted specifically for printing. Additionally, from the RECORDED INJECTIONS in the MENU, you can export your injection history into a PDF document or a CSV file, which can be printed or shared further.

    When recording my injections, what do the 3 colors represent?

    BETA track uses 3 colors to represent injection activity. Green indicates a recorded injection. Red indicates an injection not recorded. Blue indicates a scheduled injection.


    Can I install BETA track on more than one tablet device or mobile device?

    Yes. You can install BETA track on any number of tablets or mobile devices, as long as they are supported platforms.

    My computer or mobile device was lost or stolen. Can I still access my recorded injection history?

    Yes. Since your recorded injection history and other information is stored in the cloud, you can install BETA track on your new device and log in to access your information.

    My computer or mobile device was upgraded. Will be data be transferred onto my new device?

    If you are using BETA track for iPhone, iPod touch, or iPad, your data can be transferred onto your new device if you have backed up your device by syncing with iTunes or iCloud, and you did not delete the app from your device. It is very important that you sync your device regularly for this reason. If you are using BETA track for Android, you data is stored using the storage option you've selected on your Android device.

    How do I uninstall BETA track?

    To uninstall BETA track, follow the same process that you would use to remove other software or apps from your computer/mobile device. Note that uninstalling BETA track does not delete your BETA track data if you have synced it to your iCloud or Android device. You can access data by reinstalling BETA track or using it on a different device.

    How do I delete by BETA track account?

    To delete your BETA track app, permanently delete it like other software or apps on your computer/mobile device. There are no specific actions needed since your data only lives on your device or where you chose to store it. Bayer does not store any data.

    I am still having problems using BETA track. What should I do?

    If the program is not responding, you may try to restart the application or reboot your computer/mobile device. If you continue to experience problems, please contact BETAPLUS at 1-844-788-1470 (available 24/7).

    More about BETA track


    BETASERON can cause serious side effects, including:

    Depression or Suicidal Thoughts. Call your healthcare provider right away if you have any of the following symptoms, especially if they are new, worse or worry you: thoughts about suicide or dying, new or worse depression (sinking feeling or sadness), new or worse anxiety (feeling uneasy, nervous or fearful for no reason), trouble sleeping (insomnia), acting aggressive, being angry, or violent, acting on dangerous impulses, hallucinations, other unusual changes in behavior or mood.

    Please see additional Important Safety Information below.

    Be prepared for your next doctor visit

    BETAPLUS is there 24/7, BETASERON® (interferon beta-1b)

    Questions? Call 1-844-788-1470

    An MS-trained BETA Nurse is available 24/7 to answer your questions about BETASERON.

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