Betaseron

Effective Therapy.
Proven Results.

Models used for illustrative purposes only.  
 
BETASERON® (interferon beta-1b) can help

In patients with clinically isolated syndrome (CIS), BETASERON® (interferon beta-1b) is PROVEN to

In patients living with relapsing-remitting multiple sclerosis (RRMS), BETASERON is PROVEN to

PROVEN to significantly delay time to a second flare-up in patients with CIS

In a 2-year study, 292 patients with the first symptoms of MS who started treatment early with BETASERON significantly reduced their likelihood of having a second flare-up compared with 176 patients on placebo3

BETASERON cut risk of a second flare-up in half
50%
less risk*
Likelihood of a second flare-up within 2 years3
BETASERON® (interferon beta-1b) Efficacy
28%
with BETASERON
45%
with placebo
*By proportional hazard ratio regression adjusted for age/gender/steroids/T2 lesions/Gd lesions3

Indications

BETASERON® (interferon beta-1b) is a prescription medicine used to reduce the number of relapses in people with relapsing forms of multiple sclerosis (MS). This includes people who have had their first symptoms of multiple sclerosis and have an MRI consistent with multiple sclerosis. BETASERON will not cure MS but may decrease the number of flare-ups of the disease.

PROVEN to reduce the number of newly active brain lesions in patients with CIS

MRI data from a 2-year study showed that BETASERON patients with the first symptoms of MS had fewer newly active lesions at 2 years3

BETASERON reduced the number of brain lesions
56%
fewer newly active lesions3†
Newly active brain lesions:
BETASERON® (interferon beta-1b) Efficacy
3.7
with BETASERON
(292 people)
8.5
with placebo
(176 people)
Newly active lesions=nonenhancing new or enlarging T2 lesions; new Gd-enhancing lesions. (P<0.0001, hazard ratio: 0.50). The exact relationship between MRI findings and the clinical status of patients is not known3

Important Safety Information (cont'd)

Do not take BETASERON (interferon beta-1b) if you are allergic to interferon beta-1b, to another interferon beta, to human albumin, or mannitol.

BETASERON can cause serious side effects, including:

Liver Problems Including Liver Failure. Symptoms of liver problems may include yellowing of your eyes, itchy skin, feeling very tired, flu-like symptoms, nausea or vomiting, bruising easily or bleeding problems. Your healthcare provider will do blood tests to check for these problems while you take BETASERON.

PROVEN to cut frequency of flare-ups in patients with RRMS*

In a 2-year study, 124 patients taking BETASERON had 31% fewer relapses than 123 patients taking placebo13

The second main result showed the proportion of patients who had not had a flare-up at 2 years did not significantly differ between the placebo (16%) and BETASERON (25%) treatment groups5

BETASERON cut the frequency of
flare-ups
31%
fewer
flare-ups13‡
Flare-ups per year:
BETASERON® (interferon beta-1b) Efficacy
0.9
with BETASERON
1.31
with placebo
All patients were ambulatory with EDSS scores of 5.5 or less and had at least 2 acute exacerbations during the previous 2 years.5

Important Safety Information (cont'd

BETASERON can cause serious side effects, including:

Serious Allergic Reactions. Serious allergic reactions can happen quickly and may happen after your first dose of BETASERON or after you have taken BETASERON many times. Symptoms may include difficulty breathing or swallowing, swelling of the mouth or tongue, rash, itching, or skin bumps.

Understand Safety

It's important to know the possible risks and benefits of BETASERON. Make sure you talk to your doctor to understand which possible side effects are more serious than others, as well as those that are more common.

Start a Discussion

BETAPLUS is there 24/7, BETASERON® (interferon beta-1b)

Questions? Call 1-844-788-1470

Questions? Call 1-844-788-1470

An MS-trained BETA Nurse
is available 24/7 to answer your questions about BETASERON
Start a discussion, BETASERON® (interferon beta-1b)

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